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Role of aspirin in Live donor liver transplant(LDLT) in preventing acute cellular rejection(ACR)

Open Label Randomised controlled trial of role of aspirin in Live donor liver transplant(LDLT) in preventing acute cellular rejection(ACR) - Nil

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/07/055081
Enrollment
100
Registered
2023-07-11
Start date
Unknown
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C220- Liver cell carcinoma Health Condition 2: K703- Alcoholic cirrhosis of liver Health Condition 3: K721- Chronic hepatic failure Health Condition 4: K730- Chronic persistent hepatitis, notelsewhere classified Health Condition 5: K704- Alcoholic hepatic failure Health Condition 6: K712- Toxic liver disease with acute hepatitis Health Condition 7: K742- Hepatic fibrosis with hepatic sclerosis Health Condition 8: K766- Portal hypertension Health Condition 9: K720- Acute and s

Interventions

Intervention1: Tablet Ecosprin 75mg: Patients will be randomised (1:1) into 2 groups (‘Aspirin’ group and ‘no aspirin’ groups) after 2 weeks of transplant if platelets = 50,000 /ul. According to rand

Sponsors

Amrita Institute of Medical sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients who are undergoing LDLT in our institute

Exclusion criteria

Exclusion criteria: 1 . Paediatric patients (age 2. Re-transplantations 3. Patients not willing to participate in the study 4. If PLT 5. Multiorgan transplants

Design outcomes

Primary

MeasureTime frame
Primary outcomes : Occurrence of ACR both biopsy proven & clinically suspected.Timepoint: 6 months

Secondary

MeasureTime frame
1.Hepatic artery patency 2.Postoperative complications 3. Graft survival 4. Patient survival 5. Tumour recurrence for HCC patientsTimepoint: 6 months

Countries

India

Contacts

Public ContactBhanoo Tej Bathala

Amrita Institute of Medical Sciences

sudhi@aims.amrita.edu9388623851

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026