A CLINICAL TRIAL TO COMPARE THE EFFECT OF ADDITION OF LOW DOSE OF SUCCINYLCHOLINE TO PROPOFOL OR ETOMIDATE ON THE EASE OF I-GEL INSERTION IN PATIENTS UNDER GENERAL ANESTHESIA.

COMPARISON OF EFFECT OF ADDITION OF 0.25mg/kg OF SUCCINYLCHOLINE TO PROPOFOL OR ETOMIDATE ON THE EASE OF I-GEL INSERTION IN PATIENTS UNDER GENERAL ANESTHESIA- A ONE YEAR HOSPITAL BASED RANDOMISED CONTROLLED STUDY. - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/07/055017

Enrollment

Registered

2023-07-10

Start date

Unknown

Completion date

Unknown

Last updated

2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Intravenous Propofol(GROUP P): Preoxygenation will be performed for 3 minutes and premedication with midazolam 0.01 mg/kg, and fentanyl 1Âµg/kg. In Group P, Induction will be with Propo

Eligibility

Inclusion criteria

Inclusion criteria: Patients weighing between 40kg to 80kg. ASA grades 1, 2 and 3 patients of either sex, scheduled for electives surgeries under GA lasting for not more than 2 hours. The patient should be willing to provide consent.

Exclusion criteria

Exclusion criteria: Pharyngeal pathology. Any anatomical abnormality of mouth, pharynx and larynx. Risk of aspiration (History of gastroesophageal reflux or upper gastrointestinal surgery). Full stomach (pregnancy, hiatal hernia), high airway resistance difficult airway, low pulmonary compliance (severe obesity). previous history of hypersensitivity to any of study drugs previous history of malignant hyperthermia.

Design outcomes

Primary

Measure	Time frame
To compare the ease of I-GEL insertion in patients receiving 0.25mg/kg of succinylcholine to propofol (Group P) or etomidate (Group E) as the induction agent.Timepoint: Time taken for I-GEL insertion. 0- 10 seconds 11- 20 seconds 21- 30 seconds 31- 40 seconds Number of attempts 1 attempt greater than or equal to 2 attempts Failure	—

Secondary

Measure	Time frame
To assess hemodynamic changes (Systolic Blood Pressure, Diastolic Blood Pressure, Mean Arterial Pressure, Heart Rate, SpO2) following anaesthesia induction & I-GEL insertion & to study any postoperative complications (Sore-throat, Dysphagia, Dysphonia, Numbness in Tongue or Oropharynx) in patients receiving 0.25mg/kg of succinylcholine to propofol (Group P) or etomidate (Group E) as the induction agent.Timepoint: Hemodynamic Changes- 1 minute before induction After induction After I-GEL insertion After one minute After two minutes After three minutes Post Op Complications- one hour after end of surgery	—

Measure

Time frame

To assess hemodynamic changes (Systolic Blood Pressure, Diastolic Blood Pressure, Mean Arterial Pressure, Heart Rate, SpO2) following anaesthesia induction & I-GEL insertion & to study any postoperative complications (Sore-throat, Dysphagia, Dysphonia, Numbness in Tongue or Oropharynx) in patients receiving 0.25mg/kg of succinylcholine to propofol (Group P) or etomidate (Group E) as the induction agent.Timepoint: Hemodynamic Changes- 1 minute before induction After induction After I-GEL insertion After one minute After two minutes After three minutes Post Op Complications- one hour after end of surgery

—

Countries

India

Contacts

Public ContactDR NAVEEN SANTHOSH

JAWAHARLAL NEHRU MEDICAL COLLEGE

drrajeshmane@gmail.com9844131062

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026