To look at the safety and effect of injection given to the scalp of head and the medications used in treatment of pain during and after surgery that are commonly used

Effect of posterior scalp block versus skin infiltration with 0.25% bupivacaine and dexmedetomidine on pain response to craniotomy in patients undergoing elective posterior cranial fossa surgery - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/07/054959

Enrollment

Registered

2023-07-07

Start date

Unknown

Completion date

Unknown

Last updated

2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C719- Malignant neoplasm of brain, unspecified Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Scalp Block: Posterior scalp block with 15ml of 0.25% Bupivacaine and 1mcg/kg of Dexmedetomidine given just before surgical incision for one time. Control Intervention1: Skin Infiltrati

Eligibility

Inclusion criteria

Inclusion criteria: 1.Age more than 18yrs 2.ASA I and II patients 3.Undergoing elective posterior cranial fossa surgery

Exclusion criteria

Exclusion criteria: 1.Incision extending beyound the scalp block 2.Surgery extends into the supratentorial fossa 3.Pregnant women 4.History of allergy to Bupivacaine and Dexmedetomidine 5.Chronic opioids consumption patients 6.Previous history of craniotomy

Design outcomes

Primary

Measure	Time frame
To compare the effect of posterior scalp block versus skin infiltration with 0.25% Bupivacaine & Dexmedetomidine on hemodynamic response to craniotomy in patients undergoing elective posterior cranial fossa surgeryTimepoint: 1 Scalp block just before the surgery 2 Skin infiltration just before the surgery 3 Vital parameters like heart rate, blood pressure, respiratory rate, oxygen saturation for first 30 minutes.	—

Measure

Time frame

To compare the effect of posterior scalp block versus skin infiltration with 0.25% Bupivacaine & Dexmedetomidine on hemodynamic response to craniotomy in patients undergoing elective posterior cranial fossa surgeryTimepoint: 1 Scalp block just before the surgery 2 Skin infiltration just before the surgery 3 Vital parameters like heart rate, blood pressure, respiratory rate, oxygen saturation for first 30 minutes.

—

Secondary

Measure	Time frame
1.To study the time of first analgesic requirement in post operative period 2.To study the effect of the technique & the medication used on the postoperative vital parametersTimepoint: Vital parameters first 24hours post surgery 1.Heart Rate 2.Mean arterial pressure 3.Oxygenation Saturation 4.Respiratory Rate	—

Countries

India

Contacts

Public ContactDr Ashwin Pai

Kasturba Medical College,Manipal

ravitej30@gmail.com9449990778

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026