To analyze and evaluate the effects of 20% salicylic acid peel along with oral and topical antifungal therapy versus oral and topical antifungal therapy without 20% salicylic peel in the treatment of ringworm infections.

Effectiveness and safety of 20% salicylic acid peel in combination with oral and topical antifungal versus oral and topical antifungal therapy for the treatment of superficial dermatophytosis.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/07/054952

Enrollment

110

Registered

2023-07-07

Start date

Unknown

Completion date

Unknown

Last updated

2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L088- Other specified local infections of the skin and subcutaneous tissue

Interventions

Intervention1: Itrconazole 200mg and topical luliconazole 1% cream.: 110 patients taken for the study will be randomly divided into 2 groups of 55 each as per randomization tables. Patients in group 1

Eligibility

Inclusion criteria

Inclusion criteria: Patients of either sex of age more than 18 years and less than 60 years having active superficial dermatophytosis.

Exclusion criteria

Exclusion criteria: 1. Pregnant and lactating females 2. Active bacterial or viral infections 3. Involvement of major flexures 4. Patients with hypertension, diabetes, liver diseases 5. Patient who recently apply topical steroid 6. Patients younger than 18 years 7. Patients with extensive involvement (more than 20% body surface area) 8. Patients with history of hypersensitivity to formulation used in the study 9. Severe systemic illness or malignancy 10. Patients having unrealistic expectations

Design outcomes

Primary

Measure	Time frame
KOH mount-Negative or positive at end of therapy Likert scale-disease severity clinically assessed by 4 point scale in respect to erythema, induration,scaling,pustules,vesicles,maceration and papules Physicians global Assessment-Improvement graded by quantitative reduction in superficial dermatophytosis at end of 4 weeks of therapy depending on body surface area Visual Analogue scale-Patients in both groups grade their improvement from 0 to 10 as per their satisfaction at the end of therapy Timepoint: â?¢KOH mount Negative or positive KOH mount at the end of 4 weeks â?¢Likert scale (1if absent, 2 if mild, 3 if moderate, 4 if severe) at the end of 4 weeks â?¢Physicianâ??s global Assessment Excellent if more than70% reduction in tinea Good if 51-70% reduction in tinea Fair if 30-50% reduction in tinea Poor if less than 30% reduction in tinea â?¢Visual Analogue scale 7-10 if Excellent response 4-6 if Good response 0-3 if Poor response	—

Measure

Time frame

KOH mount-Negative or positive at end of therapy Likert scale-disease severity clinically assessed by 4 point scale in respect to erythema, induration,scaling,pustules,vesicles,maceration and papules Physicians global Assessment-Improvement graded by quantitative reduction in superficial dermatophytosis at end of 4 weeks of therapy depending on body surface area Visual Analogue scale-Patients in both groups grade their improvement from 0 to 10 as per their satisfaction at the end of therapy Timepoint: â?¢KOH mount Negative or positive KOH mount at the end of 4 weeks â?¢Likert scale (1if absent, 2 if mild, 3 if moderate, 4 if severe) at the end of 4 weeks â?¢Physicianâ??s global Assessment Excellent if more than70% reduction in tinea Good if 51-70% reduction in tinea Fair if 30-50% reduction in tinea Poor if less than 30% reduction in tinea â?¢Visual Analogue scale 7-10 if Excellent response 4-6 if Good response 0-3 if Poor response

—

Secondary

Measure	Time frame
noneTimepoint: none	—

Countries

India

Contacts

Public ContactPdiangty Giri Mawlong

Government medical college, Haldwani

pdiangtygmawlong29@gmail.com8571818569

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026