Comparison of two different drugs given in spinal anaesthesia in patients undergoing any surgeries below umbilicus

Comparative Study of Effects of Intrathecal 0.75% Hyperbaric Ropivacaine With Clonidine Versus 0.5% Hyperbaric Bupivacaine with Clonidine in Infraumbilical Surgeries. - nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/07/054934

Enrollment

Registered

2023-07-07

Start date

Unknown

Completion date

Unknown

Last updated

2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: group RC: patient will receive 0.75% hyperbaric Ropivacaine (3ml) with 30mcg of clonidine (0.2ml)deposited at starting of the case and observed for next 24 hours Control Intervention1:

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patient aged between 18-60 years of either sex. 2.American Society Of Anaesthesiology , physical status 1&2 3.Patients scheduled to undergo infraumbilical surgeries requiring spinal anaesthesia.

Exclusion criteria

Exclusion criteria: 1.Spine deformity 2.Coagulopathy. 3.Patient with severe hypovolemia 4.Infection at the lumbar puncture site. 5.Increased intracranial tension. 6.Neuromuscular disorders. 7. Pregnant women and lactating women 8.Patient with hypersensitivity to local anaesthetics.

Design outcomes

Primary

Measure	Time frame
To assess & compare the duration of sensory & motor block. Timepoint: sensory by pin prick method every 2 mins until the highest level is achieved then every 30min till block regress. Motor block by Modified Bromage Scale every 2mins till the bromage 3 is obtained then every 30 mins till motor block regress. 0-no motor block 1- inability to raise extended legs able to move knees & feet 2-inability to raise extended legs & knees but able to move feet 3-complete motor block	—

Measure

Time frame

To assess & compare the duration of sensory & motor block. Timepoint: sensory by pin prick method every 2 mins until the highest level is achieved then every 30min till block regress. Motor block by Modified Bromage Scale every 2mins till the bromage 3 is obtained then every 30 mins till motor block regress. 0-no motor block 1- inability to raise extended legs able to move knees & feet 2-inability to raise extended legs & knees but able to move feet 3-complete motor block

—

Secondary

Measure	Time frame
To assess & compare the time for the need of first rescue analgesia.Timepoint: first 24 hours of post operative time.	—

Countries

India

Contacts

Public ContactDr Nagaraj A S

Kempegowda Institute Of Medical Sciences

ambunagaraj67@gmail.com9916876432

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026