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Evaluation of spasm of vessels in brain and its association with perioperative complications in patients undergoing surgery through nose using an endoscope using a transcranial doppler machine.

Evaluation of cerebral vasospasm & its association with perioperative complications in patients undergoing endoscopic trans nasal surgeries using Transcranial Doppler -A Prospective observational pilot study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/07/054896
Enrollment
60
Registered
2023-07-06
Start date
Unknown
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D352- Benign neoplasm of pituitary gland

Interventions

None listed

Sponsors

DR NITHISHA ROY
Lead Sponsor
DR S MANIKANDAN
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1.Consenting adult patients undergoing endoscopic trans nasal trans-sphenoidal pituitary invasive adenomas and non- invasive pituitary adenomas at Sree Chitra Tirunal Institute for Medical Sciences and Technology. 2. Age 18-60 years 3.ASA (American Society of Anaesthesiologists) class 1 and 2 4.GCS 15/15 prior to the surgery

Exclusion criteria

Exclusion criteria: 1 .Patient refusal 2. Age less than 18 years and more than 60 years 3. Emergency surgery 4. Patients with previous history of stroke, transient ischemic attacks . 5. ASA class 3,4,5 patients 6.Patients with subarachnoid hemorrhage, vasospasm 7.Pregnant and lactating mothers 8.Transcranial surgery.

Design outcomes

Primary

MeasureTime frame
1.To assess the utility of TCD in detecting vasospasm following endoscopic trans nasal surgeries for invasive pituitary adenoma & non-invasive pituitary adenoma. 2. To clinically correlate between the TCD flow velocities & neurological complications like altered mental status, motor deficits, seizures, diabetes insipidus, CT scan evidence of infarcts or SAH. 3 .To assess the risk factors for development of vasospam & neurological deficits in this subset of patients.Timepoint: TCD will be done before induction ,within 24hours of surgery,post operative day 3 & before discharge.

Secondary

MeasureTime frame
Incidental findings are notified to surgeons & further management will be as per surgeons.Timepoint: During post operative days

Countries

India

Contacts

Public ContactDR S MANIKANDAN

SREE CHITRA TIRUNAL INSTITUTE FOR MEDICAL SCIENCES AND TECHNOLOGY

kanmanis@sctimst.ac.in9446334711

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026