Health Condition 1: L700- Acne vulgaris
Conditions
Interventions
Intervention1: ORAL ISOTRETINOIN ALONE: Oral Isotretinoin tablet 0.5 mg/kg/day for 90 days
Control Intervention1: ORAL ISOTRETINOIN WITH AZITHROMYCIN PULSE THERAPY: Oral isotretinoin tablet 0.5mg/kg/d
Sponsors
Dr Mahima Arora
Eligibility
Inclusion criteria
Inclusion criteria: A written consent for participation in the study. Patients having moderate to severe acne vulgaris.
Exclusion criteria
Exclusion criteria: Age less than 15 years. Patients having mild facial acne vulgaris, papulopustular rosacea. Married female, pregnant women and women who intend to became pregnant during the course of treatment, lactating mothers. History of macrolide sensitization, having polycystic ovary. Presence of renal and hepatic derangement, pre-existing hyperlipidemia, past history of photosensitivity, allergic reaction to the prescribed drugs. Presence of systemic disease. Drug induced acneiform eruptions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study the effect of combining oral isotretinoin to azithromycin pulse therapy in treatment of acne lesions. To compare the efficacy & safety of oral isotretinoin alone vs oral isotretinoin with azithromycin pulse therapy in the treatment of moderate to severe acne vulgaris.Timepoint: 2 weeks, 4 weeks, 6 weeks, 8weeks , 10 weeks, 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the efficacy & safety of oral isotretinoin alone vs oral isotretinoin with azithromycin pulse therapy in the treatment of moderate to severe acne vulgaris.Timepoint: 2 weeks, 4 weeks, 6 weeks, 8weeks , 10 weeks, 12 weeks | — |
Countries
India
Contacts
Public ContactDr Mahima Arora
Varun Arjun Medical College And Rohilkhand Hospital
Outcome results
None listed