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Effect of dental cleaning on markers in smokers & non-smokers

Assessing the Effectiveness of Phase-I Therapy on Interleukin-17 Levels in Smokers & Non-Smokers with Chronic Periodontitis: A Clinical Trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/07/054877
Enrollment
54
Registered
2023-07-06
Start date
Unknown
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Scaling and root planing: To measure the levels of Interleukin 17 in smokers before and after scaling and root planing Control Intervention1: Scaling and root planing: To measure the l

Sponsors

Institute of dental sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Systemically healthy patients aged 22-60 years. Patients who are current smokers and non-smokers with chronic periodontitis. Patients having probing pocket depth >= 5mm and loss of attachment >= 3mm.

Exclusion criteria

Exclusion criteria: Systemically compromised patients e.g., Diabetes mellitus, Chronic renal disease, hepatitis, HIV. Patients who underwent periodontal therapy during past 6 months. Patients on antibiotic therapy in last 6 months.

Design outcomes

Primary

MeasureTime frame
To evaluate the salivary IL-17 levels of smokers & non-smokers in chronic periodontitis patients before scaling root planing To evaluate the salivary IL-17 levels of smokers & non-smokers in chronic periodontitis patients after scaling & root planing Timepoint: 0 & 6 weeks—

Secondary

MeasureTime frame
To compare & correlate the difference in the levels of IL-17 in smokers & non-smokers before and after scaling and root planingTimepoint: 0 & 6 weeks—

Countries

India

Contacts

Public ContactAkanksha Singh

Institute of dental sciences

rikasingh22@gmail.com8171653609

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026