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Comparison of two blood clotting tests in predicting need for blood transfusion patients with tropical fever with low platelet count.

Comparison of Thromboelastography (TEG) with conventional coagulation parameters in predicting transfusion requirement in Acute Febrile Illness (AFI) patients with moderate to severe thrombocytopenia presenting to the Emergency department - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/07/054815
Enrollment
75
Registered
2023-07-05
Start date
Unknown
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A90- Dengue fever [classical dengue] Health Condition 2: B508- Other severe and complicated Plasmodium falciparum malaria Health Condition 3: A698- Other specified spirochetal infections Health Condition 4: A759- Typhus fever, unspecified

Interventions

Intervention1: NIL: NIL

Sponsors

MAC ID (Manipal Mcgill Center for Infectious Diseases)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Acute Febrile illness (Defined as fever 2) Moderate to severe thrombocytopenia defined as Platelet count

Exclusion criteria

Exclusion criteria: 1. Patients on anticoagulation or known coagulation disorder 2. Patients who have received any blood product transfusion 48 hours prior to screening 3. Patients who have undergone heparin dialysis 48 hours prior to screening

Design outcomes

Primary

MeasureTime frame
Prediction of transfusion requirement based of Thromboelastography & Conventional coagulation parametersTimepoint: Up to 48 hours from recruitment—

Secondary

MeasureTime frame
1) Incidence of any thrombotic events (Deep vein thrombosis, Pulmonary embolism, Myocardial infarction, stroke, Mesenteric ischemia, acute limb ischemia)Timepoint: up to discharge from hospital;2) Incidence of major bleeding â?? Hemoptysis, Hematemesis, Intracranial bleed, any other bleeding causing hemodynamic instability or need for transfusionTimepoint: up to 48 hours from recruitment—

Countries

India

Contacts

Public ContactRachana Bhat

Kasturba Medical College, Manipal

rachana2806@gmail.com9599460465

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026