A clinical trial to study the effects of two drugs, Misoprostol and Dinoprostone Gel in induction of labour at more than 37 weeks of Pregnancy

A Comparative Study of Sublingual Misoprostol vs. Dinoprostone Gel in Induction of Term Labour - Nil

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/07/054780

Enrollment

Registered

2023-07-05

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O80- Encounter for full-term uncomplicated delivery

Interventions

Intervention1: Misoprostol and Dinoprostone: Tab Misoprostol 25mcg given Sublingually for 4 hours and Dinoprostone Gel 0.5mg given per vaginally for 6 hours for induction of term labour. And Induction

Eligibility

Inclusion criteria

Inclusion criteria: 1. Pregnant women at term- more than or equal to 37 weeks gestation. 2. Singleton pregnancy. 3. Cephalic presentation. 4. Reactive CTG (cardiotocography) trace. 5. Bishop score

Exclusion criteria

Exclusion criteria: 1. Symptoms and signs suggestive of chorioamnionitis. 2. Prior uterine surgery (caesarean section, myomectomy),. 3. Multiparous 3 or more 4. Bad obstetric history. 5. Severe IUGR. 6. Severe oligohydramnios. 7. Contraindications to vaginal delivery like placenta previa and cephalopelvic disproportion. 8. Medical disorders complicating pregnancy, GDM, preeclampsia, heart disease, renal disease, pulmonary disease. 9. Active vaginal bleeding.

Design outcomes

Primary

Measure	Time frame
INDUCTION OF TERM LABOURTimepoint: 0,4,6,8,12 HOUR	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr Shyam Mushar

Gujarat Adani Institute of Medical Sciences

pvbhinde@yahoo.com9825225817

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026