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To compare intravenous fluid bolus and fluid plus low dose noradrenaline for preventing cardiac collapse before intubation and ventilator support

Comparison of fluid bolus and fluid bolus plus low dose noradrenaline infusion on cardiovascular collapse among critically ill adults before tracheal intubation - Nil

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/07/054773
Enrollment
136
Registered
2023-07-05
Start date
Unknown
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I504- Combined systolic (congestive) anddiastolic (congestive) heart failure

Interventions

Intervention1: ringer lactate (RL) solution, noradrenaline: Participants will be adult female and male patients aged between 18 and 60 years. Patients selected for the study will be allocated into

Sponsors

Era Lucknow Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: adult patients more than 18 years critically ill patients needing tracheal intubation in icu

Exclusion criteria

Exclusion criteria: tracheal intubation performed outside icu/hospital setting tracheal intubation during cardiac arrest patients on vasoactive medications at the time of screening hypotension SBP hypertension SBP >140 mmhg at screening urgency of tracheal intubation precludes performance of study procedures pregnant females

Design outcomes

Primary

MeasureTime frame
DECREASE IN MAP 65 MMHG (2 MIN POST INDUCTION)Timepoint: DECREASE IN MAP 65 MMHG (2 MIN POST INDUCTION)

Secondary

MeasureTime frame
. Decrease in SBP (90mmHg (2 min post induction) . New/increased vasopressor (2min post induction) .Cardiac arrest within 1 hr. . Death within 1 hr. . Ventilator-free days . noradrenaline free days . Need for RRT post intubation in ICU . Length of ICU stay . Length of hospital stay . ICU Mortality . Hospital MortalityTimepoint: Before induction and after 2 minutes of intubation

Countries

India

Contacts

Public ContactSyed Masarrat Jahan

Eras medical college and hospital

sanjay.choubey@yahoo.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026