Health Condition 1: K928- Other specified diseases of the digestive system
Conditions
Interventions
Intervention1: Intrathecal morphine injection: Intrathecal preservative free morphine at 2mcg/kg is injected with 2 ml saline in the subarachnoid space at L3-4 prior to anaesthesia(single injection on
Sponsors
Amrita Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: Patients undergoing elective laparoscopic surgery of the gastro intestinal system
Exclusion criteria
Exclusion criteria: 1. Bariatric surgery 2. Urological laparoscopic surgery - nephrectomy, adrenal and prostate surgery 3. Patients allergic to morphine 4. Patients with hepatic dysfunction(USG evidence of liver dysfunction, ALT/AST > 2 times normal); 5. Patients with cardiac dysfunction(EF 6. Patients with renal dysfunction(S. Creatinine >1.5mg/dl). 7. Preoperative coagulopathy contraindicating neuraxial blockade.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the intra operative opioid requirement.Timepoint: Duration of surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Post-operative pain 2.Hemodynamic responses 3. Adverse effects of intrathecal morphine such as drowsiness,respiratory depression(respiratory rate 8/min), pruritus,nausea, vomiting,PDPH. 4. Length of ICU stay 5. Ileus( time to tolerate oral fluids) 6. Patient satisfaction (Likeart scale) Timepoint: 1.pain at 0hr, 6hr, 12hr, 18hr, 24hrs, incentive spirometry & at ambulation. 2.Hemodynamics 1. Baseline: To 2. Port insertion: Tpi 3. Insufflation for Pneumoperitoneum: Tpp4, 4. Ligation of vessels: Tvl 5. Specimen retrieval: Tr 6. Closure: Te | — |
Countries
India
Contacts
Public ContactDrRamya Anantharaman
Amrita Institute of Medical Sciences
Outcome results
None listed