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Comparison of effects of two different routes of lignocaine during intubation

Intravenous versus Nebulized Lignocaine on Attenuation of Hemodynamic Response During Laryngoscopy and Intubation under General Anaesthesia: A Randomized Control Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/07/054687
Enrollment
98
Registered
2023-07-03
Start date
Unknown
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: To compare the effects of intravenous lignocaine versus nebulized lignocaine on attenuation of hemodynamic response during laryngoscopy and intubation Under General Anaesthesia.: Heart

Sponsors

ROHILKHAND MEDICAL COLLEGE AND HOSPITAL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade I and II Patients with Mallampati grading 1 and 2

Exclusion criteria

Exclusion criteria: Known allergy to the trial drugs Emergency surgeries or patients considered as full stomach Predicted difficult airway Patients with bronchospastic disease and known hypertensives

Design outcomes

Primary

MeasureTime frame
To compare the difference in HR SBP DBP and MAP at different intervals (before induction and after induction) in two groups. To document any complications like sore throat airway trauma etc. Timepoint: Heart rate, Systolic blood pressure, Mean arterial pressure, Diastolic blood pressure will be measured (baseline) before induction, after induction and laryngoscopy and 1,3,5 and 10 minutes after endotracheal intubation

Secondary

MeasureTime frame
o compare the difference in HR SBP DBP and MAP at different intervals (before induction and after induction) in two groups. To document any complications like sore throat airway trauma etc. Timepoint: Heart rate, Systolic blood pressure, Mean arterial pressure, Diastolic blood pressure will be measured (baseline) before induction, after induction and laryngoscopy and 1,3,5 and 10 minutes after endotracheal intubation

Countries

India

Contacts

Public ContactDR RAHUL RAJ SINGH

ROHILKHAND MEDICAL COLLEGE AND HOSPITAL

dr_malti_agrawal@yahoo.com9897897050

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026