Health Condition 1: C50- Malignant neoplasm of breast Health Condition 2: O- Medical and Surgical
Conditions
Interventions
Intervention1: SAPB (Serratus Anterior Plane Block)under vision: The serratus anterior plane block will be conducted by injecting 20 ml of 0.25 % of levobupivacaine ,through the incision, deep to serr
Sponsors
Tata Memorial Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 18â??80 years 2. ASA 1 and 2 3. All patients posted for mastectomy after chemotherapy. (post chemo mastectomy which donâ??t require peritumoral lignocaine infiltration)
Exclusion criteria
Exclusion criteria: 1. Severe cardiac disease (ischemic/valvular/failure related) which limit the functional activities of the patient. We will exclude the patients with cardiac disease with effort tolerance less than 2 floors. 2. History of chronic kidney disease, or current deranged renal functions (Current creatinine >1.2) 3. History of liver disease, or current deranged liver functions (Current AST /ALTs >2 times of normal.) 4. Patients on preoperative opioids, both strong and weak opioids like Tramadol, codeine. 5. History of allergy or contraindication to local anesthetics 6. Breast Conservative Surgeries
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare maximum NRS pain scores in patient receiving SAPB with patients receiving a placebo drug (saline) upto 24 hours.Timepoint: At 1 hr, 2 hrs & until 24 hrs | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Time of requirement of 1st rescue analgesic. 2) The occurrence of PONV within 24 hours postoperatively. 3) Sedation score 4) Comparison of NRS pain scores at 1 hour, 2 hour & next day morning post surgery. 5) Total opioid consumption (in Fentanyl equivalents) in 24 hours 6) Total opioid consumption after surgery (in fentanyl equivalents) till next day morning Timepoint: At 1 hr, 2 hrs & until 24 hrs | — |
Countries
India
Contacts
Public ContactDr Shubham D Krishan
Tata Memorial Centre
Outcome results
None listed