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In-haled salbutamol versus salbutamol with budesonide in acute asthma in children - RCT

Efficacy of nebulized salbutamol versus combination of nebulized salbutamol with budesonide in acute exacerbation of bronchial asthma in children- A randomized control trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/07/054636
Enrollment
76
Registered
2023-07-03
Start date
Unknown
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J459- Other and unspecified asthma

Interventions

Intervention1: Nebulized salbutamol plus budesonide: Intervention group will receive salbutamol plus budesonide and will be assess by using PAS score at specific time intervals and if score improves f

Sponsors

PONDICHERRY INSITUTE OF MEDICAL SCIENCIES
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Child aged 2 yrs to 15 years with acute exacerbation of bronchial asthma.

Exclusion criteria

Exclusion criteria: A. Asthmatic Children who had received any form corticosteroid therapy in less than 24 hours from the time of admission B. Children who had received salbutamol in the last 6 hours. C. Children with known history of cardiovascular disease, chronic renal disease, chronic lung disease or diabetes mellitus, congenital anomalies, genetic or metabolic disorders. D. Children with known allergy to corticosteroids E. Children with Oral candidiasis F. Children with known systemic hypertension

Design outcomes

Primary

MeasureTime frame
No distress No wheeze No dyspnea SpO2 95% No pulses paradoxus Timepoint: Response sustained 60 minutes after the last treatment

Secondary

MeasureTime frame
To compare the duration of intensive care stay among children aged 2-15 years with acute exacerbation of bronchial asthma among both groups.Timepoint: after 6 hours

Countries

India

Contacts

Public ContactBalakumaran

Pondicherry Institute Of Medical Sciences

gopalgk26@gmail.com9597264165

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026