Assessing post surgery pain relief in undergoing spine surgery with narcotic free multiple pain relief medication admister before surgery

Opioid free analgesic mixture for perioperative pain relief in spine surgeries- A prospective Randomized clinical study.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/07/054619

Enrollment

Registered

2023-07-03

Start date

Unknown

Completion date

Unknown

Last updated

2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Opioid free anaesthesia: Patient will receive intravenous paracetamol 1gm, 2gm mgso4,100mg lignocaine,8mg dexamethasone and 0.3mg/kg ketamine in 100 ml normal saline as mixture over 20

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA 1&2 physical status scheduled for elective spine surgery under general anaesthesia

Exclusion criteria

Exclusion criteria: 1.Refusal to give consent 2.contraindication to study drug 3.History or family history of malignant hyperthermia 4.ASA physical status 3 or higher were excluded 5.patients having history of convulsions meningitis infections anaemia or any cardiac hepatic renal neuromuscular disease respiratory system disease.

Design outcomes

Primary

Measure	Time frame
To compare opioid free anaesthesia technique with opioid based anaesthesia on perioperative pain relief. Intraoperative pain will be assessed using hemodynamic parameters from the time of induction till end of surgery. Postoperative pain will be assessed using 0 to 10 visual analogue score at every hour over 24 hoursTimepoint: Haemodynamic parameters before induction,after induction & after intubation,every 15minutes till theend of surgery	—

Measure

Time frame

To compare opioid free anaesthesia technique with opioid based anaesthesia on perioperative pain relief. Intraoperative pain will be assessed using hemodynamic parameters from the time of induction till end of surgery. Postoperative pain will be assessed using 0 to 10 visual analogue score at every hour over 24 hoursTimepoint: Haemodynamic parameters before induction,after induction & after intubation,every 15minutes till theend of surgery

—

Secondary

Measure	Time frame
Intraoperative & postoperative analgesic requirement Safety profile of the study drugsTimepoint: Postoperative pain will be assessed using 0to 10 VAS score at 15,30,60 minutes,2,4,6,8,10,12,16,20,24 hours.	—

Countries

India

Contacts

Public ContactDr Shankar K

Rajarajeshwari medical college and hospital

shankarkraj111@gmail.com8971719523

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026