To compare the advantage and disadvantage of using bupivacaine 0.5% heavy, isobaric levo-bupivacaine 0.5% and hyperbaric ropivacaine 0.75% in spinal anaesthesia during brachytherapy procedure

Comparison of effect of intrathecal hyperbaric bupivacaine (0.5%), hyperbaric levobupivacaine (0.5%) and hyperbaric ropivacaine (0.75%) during interventional brachytherapy: a prospective, double blind, randomized control study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/07/054588

Enrollment

Registered

2023-07-03

Start date

Unknown

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C539- Malignant neoplasm of cervix uteri, unspecified

Interventions

Intervention1: subarachnoid block: each patient will be adminstered three different study drugs during three consecutive sessions Control Intervention1: Subarachnoid block: either of Hyperbaric bupiva

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing interventional brachytherapy procedures under sole spinal anaesthesia.

Exclusion criteria

Exclusion criteria: patient refusal, allergic to study drugs, contraindication for neuraxial anasthesia, emergency surgeries.

Design outcomes

Primary

Measure	Time frame
Duration of sensory and motor blocksTimepoint: baseline (before any intervention), and intraoperatively every 2 min till adequate surgical anaesthesia achieved after IT drug administration, followed by every 10 mins after completion of surgery	—

Secondary

Measure	Time frame
Onset of sensory and motor block, VAS score, MAP and HRTimepoint: same as primary outcome	—

Countries

India

Contacts

Public ContactDr Sushma Bhatnagar

Dr BRA IRCH, AIIMS, NEW DELHI

sushmabhatnagar1@gmail.com9811326453

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026