Health Condition 1: K800- Calculus of gallbladder with acutecholecystitis
Conditions
Interventions
Intervention1: Sugammadex: Patients will receive sugammadex for reversal of neuromuscular block in dose 2mg/kg in immediate post surgery period at the time of reversal
Control Intervention1: Neostigmi
Sponsors
Lady Hardinge Medical College and Associated Hospitals
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age between 18-65 years old 2. Patients of either sex 3. ASA I and ASA II 4. Patients undergoing laparoscopic cholecystectomy
Exclusion criteria
Exclusion criteria: 1.Patients with central or peripheral nervous system diseases, such as polio, parkinsonâ??s disease, peripheral neuropathy, etc. 2.Patients with neuromuscular diseases, such as myasthenia gravis, multiple sclerosis, atrophic myotonia, etc. 3. Patients with hepatic/renal disorders 4. Patients with BMI > 30 5.Patients with known history of allergy to drugs used in the study 6.Patients taking oral contraceptive pills
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of mean percentage change in diaphragm thickening fraction (DTF) from baseline to 30 minutes post-operatively between the both groupsTimepoint: 30 minutes post-operatively | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Mean percentage change in diaphragmatic excursion (DE) from baseline to 30 minutes post-operatively 2.Mean percentage change in internal oblique muscle thickening fraction (IO TF) from baseline to 30 minutes post-operativelyTimepoint: 1.30 minutes post-operatively 2.30 minutes post-operatively | — |
Countries
India
Contacts
Public ContactDr Nishant Kumar
Lady Hardinge Medical College and Associated Hospitals
Outcome results
None listed