Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Intravenous Dexmedetomidine: Intravenous dexmedetomidine given as a bolus before spinal anaesthesia and as an infusion throughout the duration of surgery under spinal anaesthesia
Contro
Sponsors
Maulana Azad Medical College
Eligibility
Inclusion criteria
Inclusion criteria: 1.Adult patients between the age of 18-65 years scheduled to undergo elective lower limb orthopaedic surgery under spinal anaesthesia. 2.Patients belonging to American Society of Anaesthesiologists(ASA) physical status I or II. 3.Patients in whom anticipated duration of surgery 4.Patient height between 150-175cms.
Exclusion criteria
Exclusion criteria: 1.Patients having skin infection at the site of subarachnoid block. 2.Patients with thrombocytopenia/bleeding disorders/coagulopathy. 3.Patients with h/o hypersensitivity to study drug. 4.Patients having a neuromuscular/neurological disease. 5.Patients having spinal deformity. 6.Patients with cerebral palsy and mental retardation. 7.Patients who are using any opioid/sedative medication. 8.Patients with a h/o alcohol or drug abuse. 9.Patients having a BMI >30kg/m2.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of sensory block(minutes)Timepoint: Sensory block level will be assessed every 2 minutes for the initial 10 minutes of the surgery, and then every 5 minutes till the completion of the first hour of the surgery. Then after this, it will be assessed every 10 minutes for the rest of the duration of surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| Analgesic consumption over first 24 hours postoperativelyTimepoint: Total analgesic consumption of the patient in the first 24 hours post operatively will be noted.;Maximum level of sensory block achieved by spinal anaesthesiaTimepoint: Sensory block will be assessed every 2 minutes till maximum height of sensory block is attained.;Onset time & duration of motor blockade(minutes)Timepoint: Onset time of motor block is defined as the time interval(in minutes) between the intrathecal administration & attainment of Bromage score of 3. Duration of motor block is defined as the time interval(in minutes) from intrathecal administration to the point at which Bromage score is back to zero.;Onset time of sensory block(minutes)Timepoint: It is defined as the time interval(in minutes) between intrathecal administration & maximal spread of sensory block.;Post operative pain scoresTimepoint: It will be assessed post operatively just on arrival of the patient in the post anaesthesia care unit & at 4 hours, 8 hours, 12 hours and 24 hours post operatively.;Time to requirement of first analgesicTimepoint: The time interval post operatively at which the pain score(VAS score) of patient is more than or equal to 3. | — |
Countries
India
Contacts
Public ContactSimran Chahal
Maulana Azad Medical College
Outcome results
None listed