Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients >16 yrs upto 60 yrs who require AFOI for difficult airway. 2. MPG Classification III, IV 3. BMI > 30 Kg/m2 4. Mouth opening
Exclusion criteria
Exclusion criteria: 1. Age 2. MPG Classification I,II 3. BMI 4. Mouth opening > 3 fingers 5. Patients suffering from any hyperactive respiratory condition or known allergy to the taken premedications. 6. Patients with respiratory, hepatic, renal, neurological or psychiatric diseases 7. Patients with bradycardia (heart rate [HR] 8. Patients who are pregnant or with any bleeding disorder with contraindication for nasal intubation, any known allergy to one of the study medications . 9. Patients with lack of cooperation or effective communication 10. Patients with abuse to any psychotropic drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The observation of primary outcome is to assess the time of intubation with Midazolam combined with Dexmedetomidine and Midazolam combined with Clonidine as premedication in different groups.Timepoint: 18 Months. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. External manoeuvres required for manipulation of Larynx 2. Number of operators. 3. Overall intubation success rate. 4. Number of attempts taken for correct placement of tracheal tube. 5. Number of failed / oesophageal intubation. 6. Hemodynamic changes. 7. Adverse effects like nasal bleeding or dental injury.Timepoint: 18 Months. | — |
Countries
India
Contacts
Atal Bihari Vajpayee Medical University