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To assess ease of awake fibre optic intubation in patients with difficult airway using different drugs.

"A comparative study between Dexmedetomidine and Clonidine as premedication combined with Midazolam in patients of difficult airway undergoing Awake Fibreoptic Intubation." - Nil

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/06/054528
Enrollment
60
Registered
2023-06-28
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Awake Fibre optic Intubation: Awake Fibre optic Intubation is done in Maxillo facial disorders where mouth opening is restricted,mouth opening is less than 3 fingers and Mallampatti gra

Sponsors

Career Institute of Medical Sciences and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients >16 yrs upto 60 yrs who require AFOI for difficult airway. 2. MPG Classification III, IV 3. BMI > 30 Kg/m2 4. Mouth opening

Exclusion criteria

Exclusion criteria: 1. Age 2. MPG Classification I,II 3. BMI 4. Mouth opening > 3 fingers 5. Patients suffering from any hyperactive respiratory condition or known allergy to the taken premedications. 6. Patients with respiratory, hepatic, renal, neurological or psychiatric diseases 7. Patients with bradycardia (heart rate [HR] 8. Patients who are pregnant or with any bleeding disorder with contraindication for nasal intubation, any known allergy to one of the study medications . 9. Patients with lack of cooperation or effective communication 10. Patients with abuse to any psychotropic drugs.

Design outcomes

Primary

MeasureTime frame
The observation of primary outcome is to assess the time of intubation with Midazolam combined with Dexmedetomidine and Midazolam combined with Clonidine as premedication in different groups.Timepoint: 18 Months.

Secondary

MeasureTime frame
1. External manoeuvres required for manipulation of Larynx 2. Number of operators. 3. Overall intubation success rate. 4. Number of attempts taken for correct placement of tracheal tube. 5. Number of failed / oesophageal intubation. 6. Hemodynamic changes. 7. Adverse effects like nasal bleeding or dental injury.Timepoint: 18 Months.

Countries

India

Contacts

Public ContactDr. Sadikur Rahman

Atal Bihari Vajpayee Medical University

dr.priyeshlpsc@gmail.com7985975077

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026