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The aim of this study is to correlate time to achieve haemostasis and concentration of IL-8 in pulpal blood to the outcome of partial pulpotomy after 3 and 6 months follow up.

Correlation between Outcome of Pulpotomy with Time Taken for Pulpal Haemostasis and Concentration of Interleukin-8 in Cariously Exposed Mature Permanent Teeth with Symptomatic Irreversible Pulpitis : A Clinical Study .

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/06/054485
Enrollment
135
Registered
2023-06-27
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

None listed

Sponsors

Dr Saada Sulaiman
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: non-contributory medical history Deeply carious permanent molar with a preoperative provisional diagnosis of symptomatic irreversible pulpitis. History of spontaneous pain and nocturnal pain which aggravates on lying down. No history and signs of sinus tract, pus exudate, fistula, clinical swelling. Spontaneous pain and/or with sharp and lingering pain upon cold testing using Endo-Ice. Restorable tooth with probing pocket depth ( Tooth mobility within normal limits Complete caries excavation would likely result in pulpal exposure. Haemorrhage from the pulp exposure site stops with NaOCl placement within 15 minutes. The radiolucent caries penetrating the entire thickness of the dentine (extremely deep caries). Absence of periapical or furcation changes in the radiograph.

Exclusion criteria

Exclusion criteria: 1)Unexposed pulp after complete caries excavation. 2)Uncontrolled pulpal haemorrhage during the procedure lasting more than 15 minutes. 3)Absence of bleeding after pulp exposure; the pulp is judged as necrotic or partially necrotic. 4)Tooth showing negative response to cold testing or presence of sinus tract or swelling. 5)Non-restorable teeth with cracks or subgingival caries, associated sinus or swelling. 6)Tooth with poor periodontal support. 7)Prominent radiolucency at the furcation or periapical regions. 8)Presence of Immature root apices/ apical resorption. 9)Presence of internal or pathologic external root resorption, calcification or pulp canal obliteration.

Design outcomes

Primary

MeasureTime frame
correlation between pulpotomy outcome and time to achieve pulpal haemostasis. Clinical examination: visual inspection mobility testing pulp testing Radiographic outcome: No periapical or furcation changes Absence of internal and/or external root resorption Timepoint: 3 months and 6 months

Secondary

MeasureTime frame
levels of IL-8 in pulpal blood and outcome of pulpotomyTimepoint: 3 months and 6 months

Countries

India

Contacts

Public ContactDr Ruchika Roongta Nawal

Maulana azad institute of dental sciences

ruchika.roongta@gmail.com9582948894

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jul 3, 2026