Health Condition 1: K746- Other and unspecified cirrhosis ofliver
Conditions
Interventions
Intervention1: L-Taurine: L-Taurine capsule 1 gram once daily orally for 12 weeks (along with optimized standard care)
Control Intervention1: Standard care of decompensated cirrhosis: Optimized standa
Sponsors
Rajagiri Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age more than or equal to 18 years; 2. Child-Turcotte-Pugh score of 7 to 13 at presentation; 3. Fatigue Assessment Scale score more than or equal to 22
Exclusion criteria
Exclusion criteria: 1. Age less than 18 years 2. Child-Turcotte-Pugh score less than 7 or more than 13 3. Fatigue Assessment Scale score less than 22 4. Patients who were hospitalized or underwent surgery in the preceding 6 weeks 5. Sick patients who require admission to the hospital 6. Patients on psychotropic medications 7. Patients with underlying malignancy (including hepatocellular carcinoma) 8. Patients with congestive cardiac failure 9. Patients who do not consent to the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Variation in fatigue as assessed by change in Fatigue Assessment Scale scoreTimepoint: 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Variation in fatigue as assessed by change in Fatigue Assessment Scale scoreTimepoint: 6 weeks;Variation in quality of life as assessed by change in WHO QOL IndexTimepoint: 6 weeks, 12 weeks | — |
Countries
India
Contacts
Public ContactDr Susan John
Rajagiri Hospital
Outcome results
None listed