Targetting nerves supplying the knee joint for the treatment of Osteoarthritis of Knee

Comparing the effectiveness of Ultrasound guided Genicular Nerve block using 3 point approach versus 5 point approach for pain and quality of life in patients of chronic osteoarthritis of knee

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/06/054401

Enrollment

Registered

2023-06-26

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M179- Osteoarthritis of knee, unspecified

Interventions

Intervention1: GENICULAR NERVE BLOCK- 5 POINT APPROACH: THE 5 POINT APPRAOCH WILL TARGET SUPEROMEDIAL, SUPEROLATERAL AND INFEROMEDIAL BRANCHES OF GENICULAR NERVES. RECURRENT FIBULAR NERVE AND INFRAPAT

Eligibility

Inclusion criteria

Inclusion criteria: 1. COMPLAINTS OF KNEE PAIN FOR AT LEAST 6 MONTHS WITH NRS >5/10 2. DIAGNOSED CASES OF CHRONIC OSTEOARTHRITIS OF KNEE ACCORDING TO AMERICAN COLLEGE OF RHEUMATOLOGY CRITERIA 3. GRADE 2-4 OSTEOARTHRITIS ACCORDING TO KELLGREN-LAWRENCE GRADING 4. RECEIVED CONSERVATIVE TREATMENT FOR AT LEAST 3 MONTHS

Exclusion criteria

Exclusion criteria: 1. GRADE 4 OSTEOARTHRITIS WHO ARE CANDIDATES FOR TKR 2. PREVIOUS SURGICAL INTERVENTION DONE TO THE KNEE JOINT 3. PATIENTS WITH OTHER PATHOLOGY LIKE RHEUMATOID ARTHRITIS 4. PATIENTS WITH PERIPHERAL NEUROPATHY, SAPHENOUS NERVE ENTRAPMENT, RADICULOPATHY. 5. PATIENTS WITH UNCONTROLLED METABOLIC DISEASES LIKE HTN, DM. 6. PATIENTS WITH BLEEDING DIATHESIS 7. PATIENTS WITH SERIOUS NEUROLOGICAL AND PSYCHIATRIC ILLNESS

Design outcomes

Primary

Measure	Time frame
TO COMPARE THE SEVERITY OF PAIN IN PATIENTS OF CHRONIC OSTEOARTHRITIS OF KNEE AT BASELINE, AFTER 1 MONTH AND AFTER 3 MONTHS OF ULTRASOUND GUIDED GENICULAR NERVE BLOCK USING 3 POINT APPROACH VERSUS 5 POINT APPROACH USING 11-POINT NUMERICAL RATING SCALE [NRS]Timepoint: BASELINE 1 MONTH 3 MONTHS	—

Secondary

Measure	Time frame
TO COMPARE KNEE FUNCTION IN PATIENTS OF CHRONIC OSTEOARTHRITIS OF KNEE AT BASELINE AND AFTER 3 MONTHS OF ULTRASOUND GUIDED GENICULAR NERVE BLOCK USING 3 POINT APPROACH VERSUS 5 POINT APPROACH USING TIMED UP AND GO [TUG] TESTTimepoint: BASELINE 3 MONTHS;TO COMPARE QUALITY OF LIFE IN PATIENTS OF CHRONIC OSTEOARTHRITIS OF KNEE AT BASELINE AND AFTER 3 MONTHS OF ULTRASOUND GUIDED GENICULAR NERVE BLOCK USING 3 POINT APPROACH VERSUS 5 POINT APPROACH USING KNEE INJURY AND OSTEOARTHRITIS OUTCOME SCORE [KOOS]Timepoint: BASELINE 3 MONTHS	—

Measure

Time frame

TO COMPARE KNEE FUNCTION IN PATIENTS OF CHRONIC OSTEOARTHRITIS OF KNEE AT BASELINE AND AFTER 3 MONTHS OF ULTRASOUND GUIDED GENICULAR NERVE BLOCK USING 3 POINT APPROACH VERSUS 5 POINT APPROACH USING TIMED UP AND GO [TUG] TESTTimepoint: BASELINE 3 MONTHS;TO COMPARE QUALITY OF LIFE IN PATIENTS OF CHRONIC OSTEOARTHRITIS OF KNEE AT BASELINE AND AFTER 3 MONTHS OF ULTRASOUND GUIDED GENICULAR NERVE BLOCK USING 3 POINT APPROACH VERSUS 5 POINT APPROACH USING KNEE INJURY AND OSTEOARTHRITIS OUTCOME SCORE [KOOS]Timepoint: BASELINE 3 MONTHS

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Countries

India

Contacts

Public ContactMEGHA BHARGAVA

ALL INDIA INSTITUTE OF MEDICAL SCIENCES, JODHPUR

meghabhargava@outlook.in9811921802

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 6, 2026