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Study to compare between Levobupivacaine and Ropivacaine in infra-umbilical surgeries for epidural anaesthesia

A Prospective comparative study of Levobupivacaine Hydrochloride 0.5% with Ropivacaine Hydrochloride 0.75% for peri-operative epidural anaesthesia in infra-umbilical surgeries - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/06/054380
Enrollment
142
Registered
2023-06-23
Start date
Unknown
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N813- Complete uterovaginal prolapse Health Condition 2: S720- Fracture of head and neck of femur Health Condition 3: S724- Fracture of lower end of femur Health Condition 4: S820- Fracture of patella Health Condition 5: S723- Fracture of shaft of femur Health Condition 6: S822- Fracture of shaft of tibia Health Condition 7: N433- Hydrocele, unspecified Health Condition 8: S722- Subtrochanteric fracture of femur Health Condition 9: K409- Unilateral inguinal hernia, without ob

Interventions

Intervention1: Levobupivacaine Hydrochloride: 15 mL of 0.5% Levobupivacaine Hydrochloride (75 mg) single dose for Infra Umbilical Surgeries under Epidural Anaesthesia Control Intervention1: Ropivacain

Sponsors

Dr Shreya Putta
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing a given Infra umbilical surgeries giving consent to participate in study. Age between 18 to 60 years. ASA grade I and grade II

Exclusion criteria

Exclusion criteria: Patients not giving consent to participate in the study. ASA grade III and IV Patients with respiratory, cardiovascular, hepatic and renal diseases, obesity. Age below 60 years. Any bleeding disorder and patient on anticoagulants. Neurological and musculoskeletal disease. Local infection at the injection site. History of hypersensitivity or allergy to any drug

Design outcomes

Primary

MeasureTime frame
Expected early onset of sensory & motor blockade & prolonged duration of analgesia with epidural ropivacaine 0.75%Timepoint: 24 hours

Secondary

MeasureTime frame
Expected stable haemodynamic profile & lesser side effects with epidural levobupivacaine 0.5%Timepoint: 24 hours

Countries

India

Contacts

Public ContactDr S S Yadav

Gajra Raja Medical College, Gwalior

drssy_17@yahoo.com9826284553

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026