Comparative research on the effectiveness of dexmedetomidine and local anesthesia for surgically extracting mandibular third molars

Efficacy of dexmedetomidine with local anaesthesia for surgical removal of mandibular third molars; a comparative study

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/06/054370

Enrollment

Registered

2023-06-23

Start date

Unknown

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: 2% Lignocaine with 1:200000 adrenaline and dexmedetomidine: The selected patients will be administered dexmedetomidine in combination with lignocaine 2% as an adjuvant with 1:200,000 ad

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA class I patient 2.Age group18-40 years 3.Bilateral similar impaction (with same classification and difficulty index)

Exclusion criteria

Exclusion criteria: 1.Patients with a known history of an allergy or hypersensitivity to lignocaine or dexmedetomidine, 2.Pregnant or lactating mothers 3.Patients with acute pericoronitis

Design outcomes

Primary

Measure	Time frame
Faster onset of local anaesthesia, prolonged duration of local anaesthesia, decrease in bleeding intraoperativelyTimepoint: One and half year	—

Secondary

Measure	Time frame
Better hemodynamic stabilityTimepoint: Two weeks;Decrease in bleedingTimepoint: Assessed after surgical extraction immediately;Faster action of onsetTimepoint: Once LA is injected (2-3 minutes);Patient experienceTimepoint: Post operatively 1 - 2 hours;Prolong duration of anaesthesiaTimepoint: Assessed from injecting LA to when the effect is weaned of (usually 2-3 hours)	—

Countries

India

Contacts

Public ContactDr Heena Khan

Yenepoya Dental College

joycemathias26@yahoo.com9448337826

Outcome results