Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Inhalational anesthesia during one lung ventilation: During the whole surgical duration anesthesia will be maintained using inhalational agent (Isoflurane)
Control Intervention1: Intrav
Sponsors
Jawaharlal Institute of Postgraduate Medical Education and Research
Eligibility
Inclusion criteria
Inclusion criteria: Adults aged 20-65 years ASA-PS I-III Patients undergoing elective thoracotomy for lung resection with OLV
Exclusion criteria
Exclusion criteria: Patients with severe cardiac disease, hepatic or renal dysfunction patients with a prior allergic history of any study drug Patients taking sedative, opioid or sleep aid drugs Patients with Psychiatric or neurological disorder BMI >30 kg/m2 Pregnancy History of pneumonectomy or lung volume reduction surgery patients with severe systemic infections
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare EQ5D3L scores 3 months after surgery in patients undergoing lung resection under one lung ventilation between patients administered inhalation & intravenous anesthesiaTimepoint: Outcome will be analysed after collection of data for the requisite sample size | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To compare the composite of Neurological, Cardiovascular & Pulmonary complications 2. To compare the length of hospital stay 3. To compare the need of mechanical Ventilation support required postoperatively 4. To compare the number and types of rescue strategy adopted intraoperatively: PEEP/CPAP/High FiO2/Inotropes support/ Crossover to other strategyTimepoint: Outcome will be analysed after collection of data for the requisite sample size | — |
Countries
India
Contacts
Public ContactNirusha Regmi
Jawaharlal Institute of Postgraduate Medical Education and Research
Outcome results
None listed