None listed
Conditions
Interventions
None listed
Sponsors
All India Institute of Medical Sciences Raipur
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria for Exposed group - those who are apparently healthy individuals who have been posted as part of COVID-19 duty and must be wearing masks (cloth / surgical mask / N95-FFR / PPE) continuously for at least 2 hours a day for 10 days. Health care workers include faculties, residents, nursing staffs, technicians, attendants, cleaning staffs and office staffs posted in hospital wing. Inclusion criteria for Control group - those who are apparently healthy adults who used mask intermittently and not on continuous basis for more than 2 hours a day. Family members of the hospital staffs and other workers who full fill the criteria included.
Exclusion criteria
Exclusion criteria: health workers having with history of acute or chronic respiratory illness, hemoglobinopathies, chronic inflammatory diseases, cancer, diabetes mellitus or hypertension for more than 5 years duration or with any present manifestation of microangiopathy, pregnant women. Samples insufficient for DNA extraction and If extracted DNA is not of good quality
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of serum HIF-1a levels in cases and controlTimepoint: At 12 months | — |
Secondary
| Measure | Time frame |
|---|---|
| To determine the frequency percentage of the HIF-1α mutant alleles in the study population by gene sequencingTimepoint: At 12 months | — |
Countries
India
Contacts
Public ContactDr Suprava Patel
All India Institute of Medical Sciences Raipur
Outcome results
None listed