"Effect of intrathecal clonidine and low dose morphine versus high dose morphine with hyperbaric bupivacaine in patients undergoing elective lower limb orthopaedic surgeries." A parallel arm double blind randomized controlled trial.

Effect of intrathecal clonidine and low dose morphine versus high dose morphine with hyperbaric bupivacaine in patients undergoing elective lower limb orthopaedic surgeries. A parallel arm double blind randomized controlled trial. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/06/054221

Enrollment

Registered

2023-06-21

Start date

Unknown

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: INJECTION CLONIDINE: The study adjuvant clonidine 30 mcg is added to fixed dose of 2.8ml 0.5% hyperbaric bupivacaine and 100mcg morphine intrathecally in patients undergoing elective

Eligibility

Inclusion criteria

Inclusion criteria: BMI ASA 1 and 2 patients

Exclusion criteria

Exclusion criteria: 1. Patients with allergy to drugs used in the study 2. Patients with bronchial asthma , cardiac pathology, neurologic condition and psychiatric disorder. 3. Any contraindication to subarachnoid block

Design outcomes

Primary

Measure	Time frame
Injection clonidine 30mcg with injection morphine 100mcg in intrathecal block for lower limb orthopaedic surgery prolongs sensory, motor blockade, provides better quality of analgesia post-operatively.Timepoint: Baseline	—

Secondary

Measure	Time frame
Injection clonidine 30mcg with injection morphine 100mcg in intrathecal block for lower limb orthopaedic surgery decreases the incidence of PONV, pruritis, & shivering.Timepoint: baseline	—

Countries

India

Contacts

Public ContactMOHAMMED TAHLEEL RAZA

PROFESSOR

shyamsunderkamath@yahoo.co.in9900413473

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026