Health Condition 1: - Health Condition 2: O- Medical and Surgical
Conditions
Interventions
Intervention1: Oral Labetalol: 200 mg of oral Labetalol 120 minutes before induction of anaesthesia.
Control Intervention1: Oral Ivabradine: 5 mg of oral ivabradine 120 minutes before induction of ana
Sponsors
Muthu Vignesh
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients of ASA status 1 and 2 2. Patients with airway of Mallampati grade 1 and 2 3. Patients undergo elective laparoscopic abdominal surgery under general anaesthesia
Exclusion criteria
Exclusion criteria: 1. Patients refusal for study 2. Patients of ASA physical status 3 and 4 3. Allergy to drugs under study 4. Patients with significant bradycardia, hypotension and conduction blocks 5. Patients with cardiac, hepatic and renal disorders 6. Patients with anticipated difficult intubation (Mallampati grade 3 and 4) and requiring two attempts and more than 15 seconds at intubation 7. Patients receiving treatment with either of the drug under study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess & compare the changes in hemodynamic parameters of oral ivabradine & oral labetalol during laryngoscopy & endotracheal intubation.Timepoint: 2 hours before induction of anaesthesia to 4 hours after induction or desufflation whichever comes later. | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the side effects in the form of hypotension, bradycardia & any possible side effects if anyTimepoint: 2 hours before induction of anaesthesia to 4 hours after induction or desufflation whichever comes later. | — |
Countries
India
Contacts
Public ContactArvind Kumar
Indira Gandhi Institute of Medical Sciences
Outcome results
None listed