Health Condition 1: - Health Condition 2: H953- Accidental puncture and lacerationof ear and mastoid process during a procedure Health Condition 3: K352- Acute appendicitis with generalized peritonitis Health Condition 4: K801- Calculus of gallbladder with othercholecystitis Health Condition 5: S420- Fracture of clavicle Health Condition 6: O- Medical and Surgical Health Condition 7: H708- Other mastoiditis and related conditions Health Condition 8: N390- Urinary tract infection, site notspecif
Conditions
Interventions
Intervention1: oral pregabalin: pregabalin - 150 mg by oral route 90 minutes before induction in patient udergoing general anaesthesia
Control Intervention1: nil: nil
Sponsors
Pacific Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Patients giving valid informed consent. Patients aged 18 - 60 years. Patients weighing 50-80 kgs. Patients belonging to ASA (American society of anesthesiologist) physical status Grade I and II.
Exclusion criteria
Exclusion criteria: Patient refusal Patient with ASA grade III or higher Pregnant or lactating woman. On treatment with sedatives, hypnotics, antidepressants, antipsychotic medications. Patients allergic to anaesthetic medications. History of hepatic, renal dysfunction and Ischaemic heart disease. Anticipated difficult intubation Patients weighing less than 50 kgs and more than 80 kgs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Attenuation of hemodynamic response associated with laryngoscopy & intubation. Better analgesia. Timepoint: 24months | — |
Secondary
| Measure | Time frame |
|---|---|
| Better sedation. Absence of serious side effects, if any. Timepoint: 24months | — |
Countries
India
Contacts
Public ContactDr Saloni Agrawal
Pacific Medical College And Hospital
Outcome results
None listed