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To compare Effectiveness of two drugs Esmolol and Lignocaine for decreasing the Pressor Response during artificial tube insertion in respiratory tube under General Anaesthesia.

Comparison of Intravenous Esmolol Versus Dexmedetomidine For Attenuation Of Hemodynamic Responses During Laryngoscopy And Endotracheal Intubation In Adult Patients Undergoing Laproscopic Surgeries: A Prospective Randomized, Interventional Study in deparment of anaesthesia, S.M.S. Medical Collage, Jaipur.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/06/054104
Enrollment
70
Registered
2023-06-19
Start date
Unknown
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Attenuating the pressure Response to Laryngoscopy and Endotracheal intubation under General Anaesthesia.: Attenuating the pressure Response to Laryngoscopy and Endotracheal Intubation b

Sponsors

Dr Shriphal Meena
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients belonging to American Society of Anaesthesiologist (ASA) physical status grade I and II. 2. Patients willing to give written informed consent. 3. Patients of either sex.4. Age Groups 18 to 60 years. 5. Weighing 40 to 70 kg.

Exclusion criteria

Exclusion criteria: 1. Patients having history of convulsion and history of allergy to anaesthestic agents used in study. 2. Patients with anticipated difficult intubation i.e Mallampati class 3 or more,restricted neck movement or restricted mouth opening. 3. Pregnant patients and lactating mothers.

Design outcomes

Primary

MeasureTime frame
To determine the difference in changes in Heart rate from baseline to different time intervals in the two groups.Timepoint: 0,1,3,5,10 minutes after Intubation.—

Secondary

MeasureTime frame
To determine the difference in changes in Heamodynamic Responses (SBP, DBP, MAP) from baseline to different time intervals in the two groups.Timepoint: 0,1,3,5,10 minutes after Intubation.—

Countries

India

Contacts

Public ContactDr Sovit Kumar Jain

Sawai Man Singh Medical Collage & Hospital Jaipur

dr.shriphal@gmail.com9928350391

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026