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A study to compare how good oral disintergrating film of ondansetron versus intravenous ondansetron is in the prevention of postoperative nausea and vomiting in patients undergoing oocyte retrieval procedure under intravenous sedation.

Comparing the efficacy of oral disintergrating film versus intravenous ondansetron in prophylaxis of postoperative nausea and vomiting in patients undergoing oocyte retrieval procedure under intravenous sedation(propofol based) : double blind, randomised academic trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/06/054092
Enrollment
84
Registered
2023-06-19
Start date
Unknown
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Intravenous ondanseteron: Intravenous ondansetron (4 mg diluted to 10 ml with 0.9% normal saline) given over 5 minutes, preoperatively, for prevention of postoperative nausea and vomiti

Sponsors

Yenepoya Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American society of Anaesthesiologists (ASA) PS I & II . Age- females in reproductive age group (Age-18-40 years). BMI less than 30. Infertility Ovum Pickup Procedures lasting upto 60 minutes duration. Daycare procedure / admission.

Exclusion criteria

Exclusion criteria: ASA PS • & above Participants with cardiac rhythm abnormalities BMI > 30 H/o seizures and neurological deficits Participants with severe respiratory, cardiovascular, renal and hepatic diseases Participants with prior history of PONV or anti-emetic therapy pre-operatively

Design outcomes

Primary

MeasureTime frame
To measure the efficacy of the oral disintegrating film of ondansetron in the prevention of Postoperative nausea and vomiting. Timepoint: 6 hours or till discharge of daycare patient.—

Secondary

MeasureTime frame
Measure time for rescue anti-emetic, Side effects, if any.Timepoint: 1 year—

Countries

India

Contacts

Public ContactAjmal Muhammed

Yenepoya Medical College

hidrkp@gmail.com9844774108

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026