A comparative study of Dexamethasone by two different routes as an adjuvant to Ropivacaine in USG guided supraclavicular block for upper limb surgeries

To compare the analgesic efficacy of perineural and intravenous Dexamethasone as an adjuvant to 0.5% Ropivacaine for ultrasound guided brachial plexus block for upper limb surgeries: A randomised, triple blind placebo controlled trial. - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/06/054070

Enrollment

Registered

2023-06-19

Start date

Unknown

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S423- Fracture of shaft of humerus Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: to compare analgesic efficacy of perineural vs intravenous dexamethasone in prolonging analgesia in ultrasound guided supraclavicular block: Group A includes 25 patients. We will give 1

Eligibility

Inclusion criteria

Inclusion criteria: 1.Males and females between the age group18-65 years. 2.ASA class I-II. 3.BMI 18.5-29.9. 4.Undergoing surgeries around mid-arm, elbow, forearm and hand.

Exclusion criteria

Exclusion criteria: 1.Patientâ??s refusal for block. 2.History of cardiac, renal or hepatic disease, CNS disorders, neuropathy. 3.Patients having bleeding disorders. 4. Hypersensitivity to local anaesthetics and study drugs. 5.Local infection at the site where needle for block is to be inserted. 6.Patients in whom the block effect will be partial and will require supplementary anaesthesia.

Design outcomes

Primary

Measure	Time frame
Time of first analgesic request.Timepoint: Time of first analgesic request after successful supraclavicular block.	—

Secondary

Measure	Time frame
The secondary outcome measure include the number of supplemental analgesic requirements, VAS pain, patient satisfaction, random blood sugar.Timepoint: Postoperatively the patients will be evaluated for pain at 4,6,12,18,24 hours with visual analog scale pain score. Sensory & motor blockade will be assessed every 2 min for first 20 mins, then every 5 mins till 40 mins, then every 15 mins till end of surgery & thereafter every 30 mins till recovery of sensory & motor block. Random blood sugar will be monitored every 4 hourly in post-operative period for 24 hrs. following Dexamethasone injection.	—

Measure

Time frame

The secondary outcome measure include the number of supplemental analgesic requirements, VAS pain, patient satisfaction, random blood sugar.Timepoint: Postoperatively the patients will be evaluated for pain at 4,6,12,18,24 hours with visual analog scale pain score. Sensory & motor blockade will be assessed every 2 min for first 20 mins, then every 5 mins till 40 mins, then every 15 mins till end of surgery & thereafter every 30 mins till recovery of sensory & motor block. Random blood sugar will be monitored every 4 hourly in post-operative period for 24 hrs. following Dexamethasone injection.

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Countries

India

Contacts

Public ContactDR SHYAM BHANDARI

DR RAJENDRA PRASAD GOVERNMENT MEDICAL COLLEGE TANDA AT KANGRA

dr.bhandari@yahoo.Co.in9805135129

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026