To compare the effect of two different drugs to prevent painful response on injection of muscle relaxant.

Comparison of ketamine with magnesium sulphate as pre-treatment for prevention of withdrawal response to rocuronium: a prospective randomized control trial study. - comparison of ketamine with magnesium sulphate as pretreatment for prevention of withdrawal response to rocuronium: a prospective radomized control trial study.

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/06/054052

Enrollment

Registered

2023-06-16

Start date

Unknown

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Comparision of ketamine with magnesium sulfate as pretreatment for prevention of withdrawal response to rocuronium- Prospective randomized controlled study.: Comparision of ketami

Eligibility

Inclusion criteria

Inclusion criteria: 1.age 18-60 years undergoing elective surgery. 2.american society of anesthesia I and II. 3. informed written consent from patient and attenders.

Exclusion criteria

Exclusion criteria: 1. history of allergy to drugs. 2. receiving calcium channel blockers and opioids and anticoagulants. 3.with difficult intravenous access. 4 with difficult airway.

Design outcomes

Primary

Measure	Time frame
To assess withdrawal response to rocuronium injection.Timepoint: 1hour	—

Secondary

Measure	Time frame
1.hemodynamic changes to laryngotracheal intubation. Timepoint: hemodynamic changes like tachycardia, hypertension every 15 minutes ,up to 1 hour.;2.side effects of drugTimepoint: hallucination, emergence reaction, arrhythmias, bronchospasm.	—

Countries

India

Contacts

Public ContactDr Jyothi B

karnataka institute of medical sciences

drjyothib1@gmail.com9886187056

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026