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Comparison of the Efficacy of 3 modalities for the treatment of Striae Distensae or Stretchmarks - Fractional Carbon Dioxide Laser versus Autologous Platelet Rich Plasma versus Microneedling with topical Aloe Vera Gel.

Efficacy of Fractional Carbon Dioxide Laser versus Autologous Platelet Rich Plasma versus Microneedling with topical Aloe Vera Gel in the Treatment of Striae Distensae

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/06/054031
Enrollment
108
Registered
2023-06-16
Start date
Unknown
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R234- Changes in skin texture

Interventions

Intervention1: Fractional Carbon Dioxide Laser: For 6 sittings at 3 week intervals Intervention2: Platelet Rich Plasma: For 6 sittings at 3 week intervals Intervention3: MICRONEEDLING WITH TOPICAL ALO

Sponsors

Dr Sumedha Tirthani
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients of both genders with striae Distensae of all grades over any site on the body 2. Patients who have not taken treatment for striae distensae either topppical or systemic in the past 6 months

Exclusion criteria

Exclusion criteria: 1.Patients on systemic isotretinoin or corticosteroids. 2.Patients with history of keloid formation. 3.Patients with any connective tissue disease. 4.Patients with disease affecting the wound-healing process. 5.Patients with other systemic illness – cardiac, renal, hepatic illness. 6.Severely Immunocompromised 7.Pregnancy, Lactation 8.Patients who have cold intolerance 9.Patients taking photosensitive drugs and photosensitivity 10.Patient not willing for study

Design outcomes

Primary

MeasureTime frame
1. Measurement of efficacy of modalities on the basis of quartile grading score. 2. % reduction in width of Striae 3. Patient satisfaction using Likert Satisfaction scaleTimepoint: 1. before each setting - every 3 weeks 2, 3 - at end of 6 settings and 3 weeks after the last setting - at 15 weeks

Secondary

MeasureTime frame
Post procedural adverse effects & healing effects of Fractional Carbon Dioxide Laser, PRP, and Microneedling with topical aloe vera gel in treatment of striae distensae.Timepoint: 1. before each setting - every 3 weeks, at end of 6 settings

Countries

India

Contacts

Public ContactDr. Sumedha Tirthani

R L Jalappa Hospital

yeshitss1@gmail.com9448316136

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026