THERAPEUTIC BOTULINUM TOXIN INJECTION IN MASSETER MUSCLE FOR DEEP BITE CORRECTION.

EFFECT OF INTRAMUSCULAR ADMINISTRATION OF BOTULINUM TOXIN ON TEMPORALIS AND MASSETER DURING TREATMENT IN SKELETAL DEEP BITE PATIENTS - A RANDOMIZED CONTROLLED TRIAL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/06/054024

Enrollment

Registered

2023-06-16

Start date

Unknown

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K088- Other specified disorders of teethand supporting structures

Interventions

Intervention1: Botulinum toxin i.m.: Intramuscular administration of botulinum toxin in the masseter 25 units for 1 cycle in each masseter at 3 month interval. Control Intervention1: Saline i.m.: Intr

Eligibility

Inclusion criteria

Inclusion criteria: Skeletal deep bite Reduced posterior and anterior facial height

Exclusion criteria

Exclusion criteria: Poor periodontal status Blood dyscariasis Retreatment orthodontic patients Missing posterior teeth Hypersensitivity to botulinum toxin

Design outcomes

Primary

Measure	Time frame
LAFH Posterior Dental height Mandibular Plane angle Muscle activity by EMG Muscle thickness using ultrasound Clinical overbite Timepoint: T0- before administration of botulinum toxin masseter T1- immediately after administration of botulinum toxin in the masseter T2- 3 months after administration of botulinum toxin in the masseter	—

Secondary

Measure	Time frame
masseter muscle activity via EMG masseter muscle thickness using ultrasoundTimepoint: T0- before administration of botulinum toxin T1 - immediately after	—

Countries

India

Contacts

Public ContactRama Raji Sankaranarayanan

Saveetha Institute of medical and technical sciences

harishortho@gmail.com9360575950

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026