Health Condition 1: P229- Respiratory distress of newborn, unspecified
Conditions
Interventions
Intervention1: HHHFNC- Reduced flow: 1L/kg/min for 6 hours or worsening of respiratory distress whichever occurs earlier
Control Intervention1: HHHFNC-Conventional flow: 2L/kg/min for 6 hours or worse
Sponsors
No sponsor
Eligibility
Inclusion criteria
Inclusion criteria: ï?? All neonates with gestational age >=34 weeks at birth who are started on HHHFNC as per the treating clinicianâ??s decision
Exclusion criteria
Exclusion criteria: ï?? Known structural lung malformations ï?? Persistent pulmonary hypertension requiring medical treatment ï?? Significant hemodynamic instability requiring inotrope support ï?? Neonates who have previously received HHHFNC treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in PCO2 levels in venous blood gasTimepoint: Baseline (0 hours) and 6 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| ï?? Changes in PCO2 in subsequent blood gas done within 24 hours ï?? Duration of HHHFNC support ï?? Escalation of respiratory support ï?? Etiological profile ï?? Duration of NICU days ï?? Complications while on treatment ï?? Change in respiratory status six hours after starting HHHFNC as assessed by Downeâ??s score Timepoint: . Percentage of change in PCO2 in subsequent blood gas within 24 hours . Mean duration of HHHFNC support . Mean duration of NICU days | — |
Countries
India
Contacts
Public ContactDr Lavanya B S
PSG Institute of Medical Sciences and Research
Outcome results
None listed