Health Condition 1: R098- Other specified symptoms and signsinvolving the circulatory and respiratory systems
Conditions
Interventions
Intervention1: Dexmedetomidine nebulized v/s intravenous - 1 microgram per kg body weight of the patient will be given by either nebulization route or by intravenous route 30 minutes before induction.
Sponsors
Somya Pareek
Eligibility
Inclusion criteria
Inclusion criteria: 1.ASA grades 1 & 2 (American Society of Anesthesiologists physical status) 2.Age group 18- 65 years 3.Either gender 4.Patients scheduled for elective surgery under general anaesthesia with endotracheal intubation Patients fulfilling the above criteria consenting to participate in the study.
Exclusion criteria
Exclusion criteria: 1.Patient refusal. 2.Patients less than 18 years and more than 65 years of age. 3.Patients scheduled for general anaesthesia without endotracheal intubation such as mask ventilation, use of laryngeal mask airways, sedation, monitored anaesthetic care, or surgery duration more than 90mins. 4.Patients coming for surgery under regional anaesthesia. 5.Patients belonging to ASA grade >= III. 6.Patients undergoing emergency surgeries. Obese individuals (body mass index > 30 kg/m2) 7.Patients with known or unanticipated difficult intubation and those requiring more than 15secs or two attempts at laryngoscopy. 8.Patients with arrythmias. 9.Patients with known allergy to dexmedetomidine, and those on anti-hypertensive medications or preoperative drugs that could be potential confounders (clonidine, gabapentin, pregabalin, steroids)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SBP,DBP, SpO2, MAP, HRTimepoint: baseline, After giving, immediately after intubation, after 1 min, following 3 min, 5 min, 7 min, 10 min,15 min,30 min, 45 min, 60 min, 90 min | — |
Secondary
| Measure | Time frame |
|---|---|
| Post operative sore throat, analgesic dose requirements, sedationTimepoint: baseline, After giving, immediately after intubation, after 1 min, following 3 min, 5 min, 7 min, 10 min,15 min,30 min, 45 min, 60 min, 90 min | — |
Countries
India
Contacts
Public ContactDr Tejinder Singh Ajmani
Peoples College of medical sciences and research centre
Outcome results
None listed