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injection ibuprofen versus inection diclofenac for post operative pain in abdominal hysterectomy

Efficacy of intravenous ibuprofen versus intravenous diclofenac infusion for post operative analgesia in patients undergoing elective abdominal hysterectomy under spinal anaesthesia: a Prospective, Randomized, Double blinded Clinical trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/06/054001
Enrollment
100
Registered
2023-06-16
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N858- Other specified noninflammatory disorders of uterus

Interventions

Intervention1: intravenous ibuprofen: 400 mg will be given 8 hourly Control Intervention1: intravenous ibuprofen infusion versus intravenous diclofenac infusion: comparison of the above drugs for post

Sponsors

GEETANJALI MEDICAL COLLEGE AND HOSPITAL
Lead Sponsor
department of anaesthesiology geetanjali medical college and hospital
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: elective abdominal hysterectomy

Exclusion criteria

Exclusion criteria: a) Uterine malignancies b) History of allergy or hypersensitivity to ibuprofen, aspirin, NSAIDS OR COX -2 inhibitors c) Weight d) Coagulopathies e) History of gastrointestinal bleed within 6 weeks of study f) Creatinine clearance g) Patient on Warfarin, lithium or combination of ACE inhibitor and frusemide h) Other associated illness including neurological, endocrinal, cerebrovascular, cardiovascular, pulmonary, renal, hepatic, psychiatric disorder. i) Patients on opioids and chronic NSAIDS.

Design outcomes

Primary

MeasureTime frame
To compare postoperative analgesia during first 24 hours following surgery in terms of Visual Analogue Score (VAS) at rest and movement.Timepoint: 24 hours

Secondary

MeasureTime frame
1. Total dose and number of rescue analgesic requirement in 24 hours 2. Adverse effects Timepoint: 24 hours

Countries

India

Contacts

Public ContactDR ALKA CHABBRA

GEETANJALI MEDICAK AND HOSPITAL, UDAIPUR

alkachhabra2008@gmail.com8890911487

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026