It is the study done in lower limb orthopedic surgeries to assess postoperative pain. The study is done to know the efficacy of epidural fentanyl and buprenorphine as an adjuvant to ropivacaine.

A STUDY TO COMPARE EFFICACY OF EPIDURAL ROPIVACAINE WITH FENTANYL AND ROPIVACAINE WITH BUPRENORPHINE FOR POST OPERATIVE ANALGESIA IN LOWER LIMB ORTHOPEDIC SURGERIES

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/06/053993

Enrollment

Registered

2023-06-16

Start date

Unknown

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: nil: nil Control Intervention1: Group A-Ropivacaine with Fentanyl: Ropivacaine 0.1% 7ml and 30mcg fentanyl is given once in post operative period in epidural space. Control Intervention

Eligibility

Inclusion criteria

Inclusion criteria: 1 All patients posted for lower limb orthopedic surgery. 2 Patients who belongs toAmerican Society of Anaesthesiology grade I andII. 3 Age group 18-80 years.

Exclusion criteria

Exclusion criteria: 1.Patients on opioid or sedative medication in the week prior to the surgery. 2.Patients with history of alcohol or drug abuse. 3.History of coagulation disorders or on anti coagulant drug. 4.Patients who have known allergies to any of test drugs. 5.Known case of respiratory diseases. 6.Contraindications for epidural anaesthesia.

Design outcomes

Primary

Measure	Time frame
1.To study the efficacy of epidural fentanyl and buprenorphine as an adjuvant to ropivacaine for post operative analgesia. 2.To compare the duration of post operative analgesia for ropivacaine with fentanyl and ropivacaine with buprenorphine. Timepoint: 1.To study the efficacy of epidural fentanyl and buprenorphine as an adjuvant to ropivacaine for post operative analgesia at baseline.	—

Secondary

Measure	Time frame
To study systemic side effects of fentanyl and buprenorphineTimepoint: 1.To compare the duration of post operative analgesia for ropivacaine with fentanyl and ropivacaine with buprenorphine for 24 hours.	—

Countries

India

Contacts

Public ContactHarshita Muralidhar

Mahadevappa Rampure medical college

nandyalnanda@gmail.com9663420776

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026