In patients undergoing elective surgery under General Anaesthesia, we will compare three drugs, intravenous Fentanyl, intravenous Dexmeditomidine & topical Lignocaine before induction with Propofol for their effectiveness in providing better comfort during Laryngeal mask airway insertion.

A randomised double blinded study to compare the effectiveness of intravenous Fentanyl, intravenous Dexmeditomidine & topical Lignocaine for tolerance to Laryngeal mask airway insertion with Propofol induction.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/06/053992

Enrollment

147

Registered

2023-06-16

Start date

Unknown

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Laryngeal mask airway insertion: Before induction in sitting position, GROUP D as well as GROUP F will receive 2ml normal saline via atomiser and GROUP L will receive 2ml 2% Lignocaine

Eligibility

Inclusion criteria

Inclusion criteria: 1.Age 18 to 60 years. 2.Both gender. 3.Patients with ASA physical status 1 and 2. 4.Posted for elective surgery under General Anaesthesia.

Exclusion criteria

Exclusion criteria: 1.Patients with increased risk of aspiration. 2.Allergy to any of the study drugs. 3.Basal metabolic index >30 kg/m2. 4.Patient refusal. 5.Difficult airway and facial anomaly. 6.Patient with ASA physical status III & IV

Design outcomes

Primary

Measure	Time frame
To acheive optimal condition for Laryngeal mask airway insertion. Muzi & colleagues score less than or equal to 2 will be considered as optimal.Timepoint: At the time of Laryngeal mask airway insertion.	—

Secondary

Measure	Time frame
Airway complications like sore throat & hoarseness of voice or any change in voice.Timepoint: 24 hrs postoperative;To look for any side effects of study drugs.Timepoint: During LMA insertion till 24 hours postoperative .	—

Countries

India

Contacts

Public ContactNidhi Arun

Indira Gandhi Institute of Medical Sciences, Patna

rashmirakri26@gmail.com9905152996

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026