Health Condition 1: K928- Other specified diseases of the digestive system
Conditions
Interventions
Intervention1: Wet suction technique with 5-ml suction: In this method, once the stylet is removed, the needle will be flushed with 5 mL of saline replacing the air column. A 5-mL suction syringe with
Sponsors
Jayanta Samanta
Eligibility
Inclusion criteria
Inclusion criteria: 1. age >18 years 2. lymph nodes visualized on EUS and amenable for biopsy 3. Informed consent to participate in the study
Exclusion criteria
Exclusion criteria: 1. Age 2. Lymph nodes inaccessible or not visualised with EUS 3. Lymph nodes 4. international normalized ratio (INR) >1.5 5. platelet count of 6. unstable clinical conditions or any contraindication for EUS 7. Inability to give informed consent 8. Pregnancy 9. Lesions returned to be not lymph nodes will be dropped out
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint will be the rate of histological adequacy in patients with lymph nodes who underwent EUS-FNB using 22-G FNB needles with the conventional stylet slow-pull or the wet aspiration with varying suction pressure.Timepoint: At baseline - during tissue acquisition | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood contamination of specimensTimepoint: At baseline - during tissue acquisition;Comparison of the two techniques in terms of sensitivity, specificity, negative likelihood ratio, positive likelihood ratio & accuracy.Timepoint: At baseline - during tissue acquisition;Specimen adequacyTimepoint: At baseline - during tissue acquisition | — |
Countries
India
Contacts
Public ContactJayanta Samanta
Post Graduate Institute of Medical Education and Research, Chandigarh
Outcome results
None listed