Health Condition 1: J219- Acute bronchiolitis, unspecified
Conditions
Interventions
Intervention1: Nebulisation with N-Acetylcysteine: Nebulisation with N-Acetylcysteine in the treatment of acute bronchiolitis in children aged 2 to 24 months.
Intervention2: Nebulisation with 3% Hyper
Sponsors
Motilal Nehru Medical College Prayagraj Uttar Pradesh
Eligibility
Inclusion criteria
Inclusion criteria: 1.Hospitalized children,aged 2 to 24 month with clinical diagnosis of acute bronchiolitis. 2.Clinical severity score >3.
Exclusion criteria
Exclusion criteria: 1.History of N-Acetylcysteine and corticosteroid intake in last 4 week. 2.Chronic cardiopulmonary disease eg.congenital heart disease or chronic lung disease. 3.Known immunodeficiency state. 4.Family history of atopy,history of recurrent nebulization. 5.History of mechanical ventilation in neonatal period. 6.Critically sick patients at time of admission.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome will be in form of day of clinical improvement according to clinical severity scoring (score3).Timepoint: 1 year | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Total length of hospital stay. 2.Patients requiring bronchodilator in N-Acetylcysteine group and 3% hypertonic saline group. 3.Patients requiring CPAP support in each group and the day of start of it. 4.Side effects of nebulised drugs.Timepoint: 1 year | — |
Countries
India
Contacts
Public ContactBhupendra Kumar
Motilal Nehru Medical College Prayagraj
Outcome results
None listed