Effect of Hyaluronic Acid with PRF and PRF alone in the management of intrabony defects with the help of cone beam computed tomography

Evaluation of Hyaluronic Acid in combination with PRF and PRF alone assessed by cone beam computed tomography in the management of intrabony defects: A randomized controlled trial

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/06/053875

Enrollment

Registered

2023-06-14

Start date

Unknown

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: hyaluronic acid and prf: The patients will be given 2% Lignocaine Injection with adrenaline. Patients allocated to group I that is control group, having intrabony defects will be treate

Eligibility

Inclusion criteria

Inclusion criteria: Systemically healthy patients. Patients with mild to moderate chronic periodontitis with 2 & 3 walled intrabony defects. Full mouth plaque scores should be less than 15%.

Exclusion criteria

Exclusion criteria: Patients who underwent flap surgery within 1year. Teeth indicated for extraction. Patients having habit of consuming tobacco in any form. Patients having any systemic or local immunodeficiency. Pregnant and lactating women. Patients on any drug therapy which may affect the outcome of present study.

Design outcomes

Primary

Measure	Time frame
Evaluation of efficacy of Hyaluronic Acid in combination with PRF in intrabony defects clinically by measuring probing depth, relative attachment loss, plaque index and gingival index. 2)To evaluate the radiographic defect fill with the use of Hyaluronic Acid in combination with PRF and PRF alone in intrabony defects by measuring defect depth, mesio-lingual defect width and bucco-lingual defect width.Timepoint: baseline and 6 months	—

Measure

Time frame

Evaluation of efficacy of Hyaluronic Acid in combination with PRF in intrabony defects clinically by measuring probing depth, relative attachment loss, plaque index and gingival index. 2)To evaluate the radiographic defect fill with the use of Hyaluronic Acid in combination with PRF and PRF alone in intrabony defects by measuring defect depth, mesio-lingual defect width and bucco-lingual defect width.Timepoint: baseline and 6 months

—

Secondary

Measure	Time frame
Evaluating the efficacy of Hyaluronic Acid in combination with PRF and PRF alone in intrabony defects, clinically by measuring clinical attachment loss, relative attachment loss, plaque index and gingival index and radiographically by measuring defect depth, mesio-lingual defect depth and bucco-lingual defect depthTimepoint: baseline and 6 months	—

Countries

India

Contacts

Public ContactDR SALMAN ANSARI

SWARGIYA DADASAHEB KALMEGH SMRUTI DENTAL COLLEGE AND HOSPITAL

salman.ansari@sdk-dentalcollege.edu.in9665063023

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026