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Comparison of action & side effects of three different doses of drugs that numb pain sensation in the technique used to block the nerves supplying the upper limb

Comparing the Dynamics & Complication Profile of Three Different Local Anaesthetic Volumes for Selective Truncal Brachial Plexus Block A Randomized Comparative Study

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/06/053862
Enrollment
126
Registered
2023-06-14
Start date
Unknown
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M958- Other specified acquired deformities of musculoskeletal system

Interventions

Intervention1: Group 10 ml: Group A will receive 10 ml of local anaesthetic (mixture of 2 % lignocaine with adrenaline and 0.5 % bupivacaine) 3 ml into upper trunk, 3 ml into middle trunk and 4 ml int

Sponsors

Mahatma Gandhi Medical College and Research Institute
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Elective right sided upper limb bony surgeries of humerus, elbow and forearm under brachial plexus block 2. American Society of Anaesthesiologist physical status 1-3

Exclusion criteria

Exclusion criteria: 1.Patients with fractures of the clavicle, 2. BMI > 30, 3.Patients with rib fractures, 4. Pre-existing respiratory disorders, 5. Patients with coagulopathy and pre-existing nerve deficits of the brachial plexus

Design outcomes

Primary

MeasureTime frame
Incidence of phrenic nerve palsy: Reduction in the hemi diaphragmatic excursion by at least 75 % from the baseline value during deep breathing Timepoint: 30 minutes post block

Secondary

MeasureTime frame
Duration of analgesia: Time interval between needle removal & patient reported painTimepoint: The time patient reports pain is taken as the time point for assessment of duration of analgesia;Duration of the motor block: Time to recover to 5 kg of hand grip strength assessed using dynamometerTimepoint: Every hour for the first 12 hours & every 4 hours for the next 12 hours;Time to complete conduction blockade of terminal branches of brachial plexus: Time to reach a total composite score of 20/20 of complete sensory & motor blockade assessed at specific dermatome & muscle function of five terminal branches of the brachial plexusTimepoint: 10,20 & 30 minutes post block

Countries

India

Contacts

Public ContactDr Charulatha R

Mahatma Gandhi Medical College and Research Institute

ravindrancharulatha@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026