A study comparing 20% albumin with crystalloids in the treatment of critical phase of dengue fever in children between the ages of 1 and 12 years

Comparison of 20%Albumin & Crystalloids in Management of Critical Phase of Dengue Fever in Children Between Age Group 1-12years- A Randomized Controlled Trial

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/06/053816

Enrollment

Registered

2023-06-13

Start date

Unknown

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B349- Viral infection, unspecified

Interventions

Intervention1: 20% Albumin: 20% Albumin at a dose of 1gram/kg/dose over 4 to 6 hours Control Intervention1: Crystalloids: Crystalloids as per guidelines of management of dengue shock syndrome

Eligibility

Inclusion criteria

Inclusion criteria: Microbiologically proven Dengue Fever

Exclusion criteria

Exclusion criteria: Age less than 1 year and age more than 12 years Patients who are in recovery phase Patients having known allergy to inj albumin

Design outcomes

Primary

Measure	Time frame
To compare the efficacy of 20% albumin vs Crystalloid infusion as a treatment modality in critical phase of Dengue FeverTimepoint: baseline assessment of blood pressure, hematocrit levels, urine output,serial complete blood hemogram at 2hrs,4hrs,8hrs,12hrs,18hrs,24hrs, 48hrs, 72 hrs	—

Secondary

Measure	Time frame
To compare the length of stay in PICU & early recovery To study the effect on mortality To study the side effects of albuminTimepoint: Assesment of overall recovery & prognosis at the end of 4 days, 7 days , 10 days & 14 days	—

Countries

India

Contacts

Public ContactDr Pavandev

Government Medical College and Hospital Aurangabad

kshirsagarshilpa1974@gmail.com9823078722

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026