FindTrial
Sign In

Diaphragm thickness fraction as a predictor of successful weaning

TO COMPARE EFFICIENCY OF DIAPHRAGM THICKNESS FRACTION PLUS CONVENTIONAL OBJECTIVE WEANING CRITERIA WITH CONVENTIONAL OBJECTIVE WEANING CRITERIA AS A PREDICTOR OF SUCCESSFUL WEANING: A RANDOMIZED CONTROL STUDY

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/06/053777
Enrollment
300
Registered
2023-06-12
Start date
Unknown
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J22- Unspecified acute lower respiratory infection

Interventions

Intervention1: Diaphragm Thickness Fraction: In the intervention group patients will be extubated if the ultrasound guided measured diaphragm thickness fraction is more than 26%. Control Intervention1

Sponsors

None
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1.Age >=18 years 2.Duration of mechanical ventilation longer than 24 hour 3.Planned for weaning

Exclusion criteria

Exclusion criteria: Exclusion criteria: 1.Patients aged 2.Duration of mechanical ventilation less than 24 hour 3.Preexisting diaphragm disease, increased intra-abdominal pressure, phrenic nerve palsy, any breach in skin preventing DUS examination 4.Extremely critical patients

Design outcomes

Primary

MeasureTime frame
1.Duration of weaning from start of spontaneous breathing trial to extubation 2.Reintubation within 48 hours following extubation Timepoint: 1.Baseline 2.48 hours following extubation—

Secondary

MeasureTime frame
1.Incidence of ventilator associated pneumonia 2.Length of ICU stay 3.Length of hospital stay Timepoint: After extubation—

Countries

India

Contacts

Public ContactShailesh Kumar Sahu

Dr B L Kapur Memorial Hospital

rajeshmaitree2000@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026