Health Condition 1: L989- Disorder of the skin and subcutaneous tissue, unspecified
Conditions
Interventions
None listed
Sponsors
GOVERMENT MEDICAL COLLEGE SRINAGAR
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patients suspected of having cutaneous adverse drug reactions involving delayed hypersensitivity mechanism based on history, time course and clinical pattern. 2) Patients aged above 12 years irrespective of gender. 3) Patients belonging to ethnic Kashmiri population. 4) Those giving willful consent to dermatological examination.
Exclusion criteria
Exclusion criteria: EXCLUSION CRITERIA 1) Patients with active drug eruption. 2) Those having CADRs involving immediate hypersensitivity reaction/ mechanism, based on history, time course and clinical pattern such as urticaria, angioedema and anaphylaxis 3) Non-immunological or pseudo-anaphlactoid reactions 4) Use of topical corticosteroids over patch test site and or away from test site within two weeks of patch test 5) Those receiving systemic treatment such as corticosteroids, immuno- suppressants and phototherapy. 6) Those on antihistamines in preceding two weeks. 7) Rash due to viral infections and non-drug allergens. 8) Patients with known allergy to patch test materials i.e. adhesive tape (micropore), patch test chambers. 9) Those below 12 years of age. 10) Pregnant and lactating females.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the patch test sensitivity in patients with cutaneous adverse drug reactions using commercially available standardized antigens (10% in petrolatum or water). Compare the rate of positivity obtained by using standardized patch test antigen (10%) with that of patch test antigens prepared from the suspected commercial drug diluted to 10% and 30% in petrolatum or water.Timepoint: 2yrs | — |
Secondary
| Measure | Time frame |
|---|---|
| â?¢ To study the clinic-demographic profile and dermoscopic findings in patients with cutaneous adverse drug reaction attending a tertiary care hospital. â?¢ To evaluate the role of dermoscopy in the interpretation of patch tests and describe the main findings of the reaction. Timepoint: 2yrs | — |
Countries
India
Contacts
Public ContactShagufta parveen rather
Government medical college Srinagar
Outcome results
None listed