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Identification of diagnostic biomarkers in tubercular uveitis patients.

Identification of diagnostic biomarkers in vitreous/ aqueous fluid of ocular tuberculosis patients. - NIL

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/06/053753
Enrollment
220
Registered
2023-06-12
Start date
Unknown
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H438- Other disorders of vitreous body

Interventions

None listed

Sponsors

Indian Council of Medical Research (ICMR), New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: -Cases of tubercular or suspected tubercular posterior uveitis satisfying definition of ‘persistent’, ‘severe’ or ‘atypical’ presentation. -Cases of idiopathic macular hole, non-inflammatory ERM and RRD posted for vitrectomy (negative controls) -Cases of clinical endophthalmitis planned for vitrectomy (positive control).

Exclusion criteria

Exclusion criteria: -Patients not consenting for the study. -Pregnant lady -Age below 18 years

Design outcomes

Primary

MeasureTime frame
Any suitable biomarker protein after validation with the described techniques can be further used in the development of an early diagnostic ELISA kits or rapid diagnostic kits & can be used as potential drug targets.Timepoint: After completion of whole study as well as data analysis we will be able to find a protein of interest that may be further taken to prepare an early diagnostic ELISA kit or rapid diagnostic kit.—

Secondary

MeasureTime frame
NilTimepoint: Nil—

Countries

India

Contacts

Public ContactDr Himansu Sekhar Behera

L V Prasad Eye Institute

himansu@lvpei.org8851165153

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026