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To compare two drugs hyperbaric levobupivacaine and hyperbaric bupivacaine for cesarean section

TO COMPARE THE EFFICACY OF INTRATHECAL HYPERBARIC LEVOBUPIVACAINE VERSUS HYPERBARIC BUPIVACAINE IN PATIENTS UNDERGOING ELECTIVE LOWER SEGMENT CAESAREAN SECTION

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/06/053720
Enrollment
60
Registered
2023-06-09
Start date
Unknown
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: - Health Condition 3: O- Medical and Surgical

Interventions

Intervention1: Intrathecal block: We will give hyperbaric levobupivacaine in intrathecal space for caesarean section ,12mg,and various parameters will be noted and compared for 60mins with other group

Sponsors

Dr Reena makhni
Lead Sponsor
Dr kamal Jyoti kashyap
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Age group between 18-40years of female sex,ASA grade 2 pregnant patients at term undergoing caesarean section with normal neurological status and cooperative patients

Exclusion criteria

Exclusion criteria: Patients refusal for written consent for spinal anaesthesia,any neurological disorder,any coagulation disorder, allergy to study drug, history of any coexisting diseases like IHD,impaired renal functions, rheumatoid arthritis,severe liver disease and also contraindications to regional anaesthesia

Design outcomes

Primary

MeasureTime frame
Onset & duration of sensory and motor blockade Hemodynamic changesTimepoint: Onset & duration of sensory and motor blockade for 6 hours post op and haemodynamic parameters for 24 hrs. Hemodynamic changes

Secondary

MeasureTime frame
Adverse effects like nausea, vomiting, pruritis, shivering, sedation. To assess the quality of intramuscular muscle relaxation. Time for first rescue analgesic requirements Total number of rescue analgesiaTimepoint: Time from start of procedure till 24hours post surgery

Countries

India

Contacts

Public ContactDrReena Makhni

Government medical college amritsar

reenamakhni22@yahoo.co.in9814063758

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026